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El sistema de conducción está compuesto de miocitos especializados. Los componentes y la estructura del sistema de conducción en el hombre son comparables a los encontrados en los animales utilizados normalmente en el laboratorio. Desde entonces ha sido un tema polémico, posiblemente debido al conocimiento poco preciso de las definiciones histológicas que los primeros investigadores hicieron sobre este sistema. La descripción morfológica de los nodos cardíacos y del sistema de conducción específico comenzó hace aproximadamente 100 años.
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Knowledge of the specialized myocardium can help in the development of potentially useful therapies for some forms of cardiac arrhythmia.Īl mismo tiempo que se han desarrollado las técnicas de ablación mediante catéter para el tratamiento de las arritmias, se ha producido un gran interés por la disposición anatómica del sistema de conducción cardíaco. Only at the distal ramifications of the bundle branches do the fibrous sheaths disappear, allowing continuity with the ventricular myocardium. The His bundle penetrates the right fibrous trigone, then divides into two specialized ventricular bundle branches (right and left), which also are surrounded by a fibrous sheath that separates the specialized myocytes from the ordinary myocardium. Its atrial components, the sinus node and the atrioventricular node, are in contact with atrial myocardium. The conduction system is composed of specialized myocytes. The components and structure of the specific conduction system in humans are similar to those found in commonly used laboratory animals. Since then the subject has been controversial, possibly because of the early researchers' imprecise knowledge of histology. The first descriptions of the anatomy of the nodes and atrioventricular conduction system appeared nearly 100 years ago. A indicates aorta PT, pulmonary trunk LV, left ventricle LV, left ventricle TV, tricuspid valve.Ĭoncomitant with the development of catheter ablation techniques for the treatment of atrial arrhythmias, there has been renewed interest in the morphologic arrangement of the cardiac conduction system. Note the difference in arrangement between the medial and deep layers of the left ventricle. f: dissection of the ventricular muscular fibers of an adult human heart. Note the elliptical arrangement of the network and offshoots from the edges that penetrate the myocardium (arrows). e: subendocardial arrangement of the Purkinje network in the left ventricle of a calf. d: section of a calf heart (van Gieson staining, x100) obtained after injecting Indian ink into the Purkinje network), which is enveloped at its origin by connective tissue (red). Note in B the three fascicles of the left bundle branch (arrows), and in C the moderator band (MB). Subendocardial injections of Indian ink reveal the right and left bundle branches and the Purkinje network. b and c: a fresh calf heart in which the right and left ventricles have been opened. a: diagram by Tawara showing the trifascicular arrangement of the left bundle branch in Humans.